The BEST Mac and Cheese Meatloaf Casserole
The BEST Mac and Cheese Meatloaf Casserole is a delightful dish that brings together two beloved comfort foods in one amazing recipe. This casserole is perfect for family dinners, potlucks, or any occasion where you want to impress your guests with minimal effort. With its flavorful meatloaf base topped with creamy mac and cheese, this dish stands out for its rich taste and satisfying texture.
Why You’ll Love This Recipe
- Hearty Combination: The blend of meatloaf and mac and cheese makes this casserole a filling meal that satisfies both kids and adults.
- Easy to Prepare: With straightforward steps, you can whip up this dish without stress, making it perfect for weeknight dinners.
- Versatile Serving Options: Serve it hot from the oven or enjoy it as leftovers; it tastes great either way!
- Crowd-Pleaser: This casserole is sure to impress at gatherings, providing a unique twist on traditional favorites.
- Customizable Ingredients: Feel free to adapt the recipe by adding vegetables or different cheeses to suit your family’s taste.
Tools and Preparation
To make The BEST Mac and Cheese Meatloaf Casserole, you’ll need some essential kitchen tools. Having the right equipment will ensure smooth preparation and cooking.
Essential Tools and Equipment
- Baking dish (9×13 inches)
- Mixing bowls
- Medium saucepan
- Whisk
- Measuring cups and spoons
Importance of Each Tool
- Baking dish: A sturdy baking dish allows even cooking and easy serving of your casserole.
- Mixing bowls: These are essential for combining ingredients thoroughly, ensuring every bite is flavorful.
- Whisk: A whisk helps achieve a smooth cheese sauce without lumps, resulting in a creamy texture.

Ingredients
A delicious and hearty casserole combining classic mac and cheese with a flavorful meatloaf layer, perfect for a comforting family meal.
For the Meatloaf Layer:
- 1 ½ pounds ground beef
- 1 cup breadcrumbs
- 1 egg
- ½ cup milk
- 1 small onion, finely chopped
- 1 teaspoon garlic powder
- 1 teaspoon salt
- ½ teaspoon black pepper
- ½ cup barbecue sauce (for topping)
For the Mac and Cheese Layer:
- 2 cups elbow macaroni
- 2 tablespoons butter
- 2 tablespoons all-purpose flour
- 2 cups milk
- 2 cups shredded cheddar cheese
- ½ teaspoon salt
- ¼ teaspoon paprika (optional)
How to Make The BEST Mac and Cheese Meatloaf Casserole
Step 1: Preheat the Oven
Preheat your oven to 375°F (190°C). Lightly grease a 9×13-inch baking dish to prevent sticking.
Step 2: Prepare the Meatloaf Layer
- In a large bowl, combine:
- Ground beef
- Breadcrumbs
- Egg
- Milk
- Chopped onion
- Garlic powder
- Salt
-
Black pepper
-
Mix until evenly combined.
- Press the meat mixture firmly into the bottom of the prepared baking dish to form an even layer.
- Spread barbecue sauce evenly over the top of the meat mixture.
Step 3: Bake the Meatloaf Base
Bake for 25 minutes to allow the meat to start setting while you prepare the macaroni.
Step 4: Cook the Macaroni
Meanwhile, cook elbow macaroni according to package directions. Drain and set aside.
Step 5: Make the Cheese Sauce
- In a medium saucepan over medium heat, melt butter.
- Whisk in flour and cook for 1 minute while stirring constantly.
- Slowly add milk while continuing to whisk until thickened into a smooth sauce.
- Remove from heat and stir in shredded cheddar cheese, salt, and paprika (if using) until smooth and creamy.
Step 6: Combine Macaroni with Cheese Sauce
Fold cooked macaroni into the cheese sauce until well coated.
Step 7: Assemble Casserole
Carefully spoon mac and cheese over the partially baked meatloaf layer, smoothing it into an even layer.
Step 8: Final Bake
Return dish to oven and bake for an additional 15-20 minutes or until top is golden brown and bubbling.
Step 9: Serve
Let casserole rest for about 5 minutes before slicing into portions. Enjoy your delicious meal!
How to Serve The BEST Mac and Cheese Meatloaf Casserole
Serving The BEST Mac and Cheese Meatloaf Casserole is an opportunity to elevate your family meal. With its hearty layers of meatloaf and creamy mac and cheese, you can create a delightful dining experience. Here are some serving suggestions to consider.
Pair with a Fresh Salad
- Caesar Salad: Crisp romaine lettuce topped with Parmesan cheese, croutons, and a tangy dressing.
- Garden Salad: A mix of fresh greens, cherry tomatoes, cucumbers, and your choice of dressing for a refreshing contrast.
- Coleslaw: Crunchy cabbage slaw adds a nice crunch and balances the rich flavors of the casserole.
Add Some Bread
- Garlic Bread: Warm, buttery garlic bread complements the casserole beautifully.
- Dinner Rolls: Soft dinner rolls are perfect for scooping up the cheesy goodness.
- Cornbread: Slightly sweet cornbread pairs well with the savory meatloaf layer.
Offer Condiments
- Hot Sauce: A dash of hot sauce can enhance the flavor for those who enjoy a bit of heat.
- BBQ Sauce: Serve extra barbecue sauce on the side for dipping or drizzling over each slice.
How to Perfect The BEST Mac and Cheese Meatloaf Casserole
Achieving perfection with The BEST Mac and Cheese Meatloaf Casserole is all about attention to detail. Here are some essential tips to ensure your dish turns out amazing every time.
- Use Fresh Ingredients: Opt for fresh ground beef and real cheese for superior flavor.
- Don’t Overcook the Pasta: Cook macaroni until just al dente; it will soften further in the oven.
- Layer Evenly: Spread both layers evenly in the dish for consistent cooking and flavor distribution.
- Let It Rest: Allowing the casserole to rest after baking helps it set, making it easier to slice.
- Experiment with Cheeses: Try mixing different cheeses like mozzarella or gouda for added depth of flavor.
Best Side Dishes for The BEST Mac and Cheese Meatloaf Casserole
To complement The BEST Mac and Cheese Meatloaf Casserole, consider these delightful side dishes. Each adds something special without overpowering the main dish.
- Roasted Vegetables: Toss seasonal vegetables in olive oil, salt, and pepper; roast until tender for a healthy side.
- Steamed Green Beans: Lightly steamed green beans provide a bright pop of color and freshness on the plate.
- Mashed Potatoes: Creamy mashed potatoes are always a hit alongside meatloaf; add garlic or herbs for flair.
- Baked Beans: Sweet baked beans add a comforting taste that pairs well with hearty casseroles.
- Potato Wedges: Crispy potato wedges seasoned with herbs make a fantastic finger food option.
- Corn on the Cob: Grilled or boiled corn on the cob brings sweetness that complements savory dishes perfectly.
Common Mistakes to Avoid
When making The BEST Mac and Cheese Meatloaf Casserole, it’s easy to overlook a few details. Here are some common mistakes to watch out for:
- Not Preheating the Oven: Skipping this step can lead to uneven cooking. Always preheat your oven to ensure even baking.
- Using Cold Ingredients: Starting with cold eggs or milk can affect your meatloaf and cheese sauce texture. Let ingredients come to room temperature for best results.
- Overmixing the Meatloaf: Mixing too much can make the meatloaf tough. Combine until just mixed to keep it tender.
- Skipping the Resting Time: Cutting into the casserole immediately can cause it to fall apart. Allow it to rest for a few minutes before serving for better slices.
- Not Measuring Ingredients Accurately: Using too much or too little of key components can alter flavors and textures. Always measure carefully for consistent results.

Storage & Reheating Instructions
Refrigerator Storage
- Store leftovers in an airtight container for up to 3 days.
- Make sure the casserole is completely cool before sealing to maintain freshness.
Freezing The BEST Mac and Cheese Meatloaf Casserole
- Freeze in an airtight container or heavy-duty freezer bag for up to 3 months.
- Label the container with the date for easy tracking.
Reheating The BEST Mac and Cheese Meatloaf Casserole
- Oven: Preheat to 350°F (175°C) and cover with aluminum foil. Heat for about 20-25 minutes or until warmed through.
- Microwave: Place a serving in a microwave-safe dish, cover loosely, and heat on high for 1-2 minutes, stirring halfway.
- Stovetop: Warm individual portions in a skillet over low heat, stirring occasionally until heated through.
Frequently Asked Questions
If you have questions about The BEST Mac and Cheese Meatloaf Casserole, here are some common ones:
Can I use ground turkey instead of beef?
Yes, ground turkey works well as a lighter alternative and still provides great flavor.
How do I customize the cheese sauce?
Feel free to mix different cheeses like mozzarella or pepper jack for varied flavors in your mac and cheese layer.
What can I serve with The BEST Mac and Cheese Meatloaf Casserole?
Pair this dish with a fresh salad or steamed vegetables for a balanced meal.
Can I prepare this casserole ahead of time?
Absolutely! You can assemble it a day in advance and refrigerate before baking.
Final Thoughts
The BEST Mac and Cheese Meatloaf Casserole is a delightful blend of comforting flavors that everyone will love. It’s perfect for family dinners or gatherings, and you can easily customize it with your favorite ingredients. Give this recipe a try; it’s sure to become a household favorite!
The BEST Mac and Cheese Meatloaf Casserole
The BEST Mac and Cheese Meatloaf Casserole is a scrumptious fusion of two classic comfort foods, delivering a hearty meal that your family will adore. This dish features a savory meatloaf base made from ground beef, topped with creamy, cheesy macaroni. It’s perfect for busy weeknights or gatherings, combining rich flavors and satisfying textures in one easy-to-prepare casserole. Whether served fresh from the oven or enjoyed as leftovers, this delightful recipe offers a comforting taste that makes every dining experience special.
- Prep Time: 15 minutes
- Cook Time: 45 minutes
- Total Time: 1 hour
- Yield: Serves 8
- Category: Main
- Method: Baking
- Cuisine: American
Ingredients
- 1 ½ pounds ground beef
- 1 cup breadcrumbs
- 1 egg
- ½ cup milk
- 1 small onion, finely chopped
- 1 teaspoon garlic powder
- 1 teaspoon salt
- ½ teaspoon black pepper
- ½ cup barbecue sauce
- 2 cups elbow macaroni
- 2 tablespoons butter
- 2 tablespoons all-purpose flour
- 2 cups milk
- 2 cups shredded cheddar cheese
- ½ teaspoon salt
- ¼ teaspoon paprika (optional)
Instructions
- Preheat your oven to 375°F (190°C) and grease a 9×13-inch baking dish.
- In a large bowl, mix ground beef, breadcrumbs, egg, milk, chopped onion, garlic powder, salt, and black pepper until well combined. Press the mixture into the bottom of the prepared baking dish and top with barbecue sauce.
- Bake for 25 minutes.
- Cook elbow macaroni according to package instructions until al dente; drain.
- In a saucepan over medium heat, melt butter and whisk in flour. Gradually add milk while whisking until thickened. Stir in shredded cheddar cheese until smooth.
- Combine cooked macaroni with cheese sauce and pour over the meatloaf layer.
- Bake for an additional 15-20 minutes until golden brown.
Nutrition
- Serving Size: 1 serving
- Calories: 410
- Sugar: 4g
- Sodium: 680mg
- Fat: 22g
- Saturated Fat: 10g
- Unsaturated Fat: 10g
- Trans Fat: 0g
- Carbohydrates: 34g
- Fiber: 2g
- Protein: 24g
- Cholesterol: 80mg
